Neural correlates of LSD-induced, eyes-closed, psychedelic Imagery
LSD, with eyes-closed, produced marked increases in the functional connectivity between the primary visual cortex (V1) and the rest of the brain, measured with fMRI. Furthermore, these increases correlated positively with the subjective ratings of eyes-closed psychedelic imagery (r=0.74, p=0.0016), and they correlated with decreased alpha power in occipital sensors measured with MEG (r=-0.81, p=0.0015, MEG was measured approximately 90 minutes after fMRI). Since V1 is centrally involved in visual processing, these results imply that increased communication between V1 and several brain regions may underlie LSD’s characteristic effects on eyes-closed visual perception.
Leor did his BSc in Neuroscience in Tel Aviv University. Since June 2013, he has been working under the supervision of Prof. Nutt and Dr. Carhart-Harris as a research assistant, MRes student and PhD student in neuroscience as part of the Beckley-Imperial Research Program. Leor specializes in analysis techniques of fMRI, and his main focus is the study of psychedelic visual imagery and its neural correlates.